Insect-derived anti-Infectives from Indonesia (Triple-In)

Insects are the most successful group of organisms on earth in terms of biodiversity. Their tremendous taxonomic and molecular diversity makes the indispensable as biological resources for natural product research.

This project aims to identify natural products by targeting insects from Indonesia that exhibit antimicrobial activity, particularly against the infective agents responsible for tuberculosis and malaria. Two approaches will be combined to perform targeted screening for novel antimicrobial peptides and small organic molecules. The analysis of hemolymph samples and defensive secretions from insects will include the use of a newly-developed portable GC-MS device that allows initial screening in the field, e.g. in the rainforest. Screens for novel antimicrobial peptides will be based on the suppression subtractive hybridization approach, a PCR-based technique which is the method of choice for the targeted identification of new effector genes. Novel antimicrobial small molecules will be synthesized de novo, and novel antimicrobial peptides will be produced as recombinant proteins. Both will be tested for their activity against human pathogenic bacteria and Plasmodium falciparum. The expertise and technologies established within the LOEWE Center for Insect Biotechnology and Bioresources in Giessen provides an ideal platform for the further development of insect-derived anti-infectives as new therapeutic entities. Our combined approaches in targeted identification of novel compounds with anti-infective activity in insects will be for the first time applied in a country that belongs to hot spots of biodiversity.

Prof. Dr. Andreas Vilcinskas, Applied Entomology, Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Aachen

Prof. Rosichon Ubaidillah, Animal Taxonomy and Entomology, Indonesian Institute of Sciences, Research Center for Biology, Gedung Widyasatwaloka, Museum Zoologicum Bogoriense

Dr. Hari Sutrisno, Entomology, Indonesian Institute of Sciences, Research Center for Biology, Gedung Widyasatwaloka, Museum Zoologicum Bogoriense

Dr. Djunijanti Peggie, Animal Taxonomy (Entomology), Indonesian Institute of Sciences, Research Center for Biology, Gedung Widyasatwaloka, Museum Zoologicum Bogoriense

Advertisements by German Universities

Hands-on Master’s programs at Hof University Graduate School

You hold a Bachelor and already gained some work experience? Kick-start your career with our exciting hands-on M.B.A. and M.Eng. programs. All programs comprise an internship – a great opportunity to ...

More

International Study Programmes at Fulda University of Applied Sciences

Study international Bachelor’s or Master’s programmes in Engineering, Business, Nutrition, Health or Humanities with a focus on practice-oriented learning.

More

Discover the top-ranked International Graduate Programs at Technische ...

19 International Master & PhD Programs at Technische Universität Kaiserslautern Application Deadline: Apr 30 & Oct 31 More information: www.uni-kl.de/en/international

More

Study in Berlin - MBA & International Master’s Programmes

Study management in English. Improve your leadership skills. Gain digital know-how. Become part of an international student body. Benefit from many corporate activities, valuable career consultation a...

More

LL.M. International Finance Program at ILF

Earn an LL.M. International Finance degree at the Institute for Law and Finance (ILF). Scholarships available! Degree conferred by Goethe University Frankfurt. For graduates from Asia holding a first ...

More

Fully-funded Climate Protection Fellowships

Climate experts (prospective leaders and postdocs) wanted! Apply now to conduct a project of your own choice in Germany. Deadline: 1. February 2023

More

Truly international – Study at ESB Business School!

Do you want to study in the heart of Germany, Europe’s strongest and most dynamic economy? Come to ESB Business School at Reutlingen University!

More
1/7

Contact

  • DAAD Regional Office Jakarta

    JI. Jend. Sudirman, Kav. 61-62, Summitmas Building 2, 14th Floor 12190 Jakarta Telephone: +62 (21) 5200 870
    Fax: +62 (21) 5252 822

    Consulting hours
    Due to the ongoing COVID-19 pandemic, we are shifting our consultation online via Microsoft Teams. CLICK HERE to make an appointment for Online Consultation with our team.

    In 2022 our office will be closed on:

    • August 17
    • October 03
    • November 01
    • December 25, 26